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Ruminococcus gnavus bacteremia associated with fecal peritonitis secondary to small bowel perforationS gene variation of HBV

Ruptured primary splenic angiosarcoma into the colon. Presentation as anal bleeding

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(Acta gastroenterol. belg., 1999, 62, 248-251)

April-June Volume 62, fasc. 2

Ruptured primary splenic angiosarcoma into the colon. Presentation as anal bleeding

J.A. Jiménez-Heffernan 1, D. Hardisson 1, M.I. Prieto-Nieto 2, E. Burgos 1. - From the Departments of (1) Pathology and (2) Surgery. University Hospital "La Paz". Madrid, Spain.

A 71-year-old woman presented with a six month history of constipation and abdominal discomfort, with anal bleeding during the last days. Ultrasonography and CT-scan of the abdomen showed a large heterogeneous mass that was located in the splenic region, but the nature and origin of the tumour could not be clearly established preoperatively. The clinical diagnosis was of abdominal tumour with colonic and splenic involvement, and a left helwcolectomy and splenectomy were performed. Pathologic examination revealed a primary angiosarcoma of the spleen with penetration and fistulization of the tumour into the large bowel. The patient received adjuvant radiation therapy, but she died of extensive metastastic disease from her primary angiosarcoma of the spleen nine months after surgery. In summary, spienic angiosarcoma is very difficult to diagnose preoperatively. This highly aggressive neoplasm has an overall poor prognosis, specially if it is associated with rupture and haemoperitoneum. As this case highlights, unusual forms of rupture may lead to atypical clinical presentations, increasing even more the ffimcufty in the diagnosis.