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Treatment with lamivudine for non-immunocompromized patients with chronic hepatitis BTrichobezoar and Rapunzel syndrome : an unusual cause of abdominal mass

Treatment with terlipressin as a bridge to liver transplantation in a patient with hepatorenal syndrome

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(Acta gastroenterol. belg., 1998, 61, 268-270)

April-June Volume 61, fasc. 2

Treatment with terlipressin as a bridge to liver transplantation in a patient with hepatorenal syndrome

0. Le Moine, A. El Nawar, R. Jagodzinski, N. Bourgeois, M. Adler, M. Gelin, and M. Cremer. - Departments of Gastroenterology and Digestive Surgery, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Hepatorenal syndrome is a rapidly lethal complication of cirrhosis. The present case provides further evidence of the efficacy of terlipressin in this context even with concomitant treatment with propranolol. A 56 year old male with HBV related cirrhosis developed renal failure characteristic of hepatorenal syndrome. He was also taking propranolol for primary prophylaxis of variceal bleeding. Terlipressin 6 mg/day was administered during haemodialysis and after 1 week plasma creatinine dropped from 6,2 to 2,8 mg%. Daily urinary volume, plasma sodium and natriuresis dramatically increased during the treatment. Discontinuation of the treatment led to a rapid relapse of renal failure (plasma creatinine from 1,8 to 2,2 mg%) and the drug was readministered until a successful liver transplantation could be performed 1 month after the beginning of the treatment. The patient has now a near normal renal function 3 months after transplantation.