|
Shopping Cart
Your Cart is currently empty.
Member Login
Sponsors & Partners
Acta Gastroenterologica Belgica is supported by grants
from its major sponsors
Acta Gastro-Enterologica Belgica is published in
partnership with the following national societies
Reviews
Diagnostic accuracy of nuclear medicine imaging in protein losing enteropathy : systematic review and meta-analysis of the literaturePrice: €10,00 |
|
| Background and Aim : Scintigraphy using Tc-99m or In-111
labeled
proteins is an important diagnostic modality for diagnosis
of protein losing enteropathy (PLE). We systematically reviewed
the available literature regarding the accuracy of scintigraphy
using
Tc-99m or In-111 labeled proteins for diagnosis of PLE.
Methods : Medline and SCOPUS were searched using ((“protein
losing”) AND (“scintigraphy” OR “Nuclear Medicine”)) as
keywords
without any language or date limit. All studies on the
accuracy
of scintigraphy using Tc-99m or In-111 labeled proteins
in PLE were included in the systematic review.
Results : Overall 12 studies were included in our study. Pooled
sensitivity and specificity were 87% [81-92%], and 62% [51-72%],
respectively. Tc-99m labeled tracers had higher sensitivity but lower
specificity compared to In-111 labeled ones. Delayed imaging
could increase the sensitivity of imaging despite the lower specificity
compared to the early images. Restriction of the analyses to
larger studies (more than 10 patients) and to studies with the gold
standard of fecal alpha1-antitrypsin did not change the pooled
indices.
Conclusion : Scintigraphy using Tc-99m or In-111 labeled
proteins
has high sensitivity for diagnosis and localization of PLE.
Using Tc-99m labeled tracers and delayed imaging can further
increase
the sensitivity. Despite the high sensitivity, specificity of
scintigraphy is suboptimal and false positive abdominal activities
can limit the usefulness of this imaging method. (Acta gastroenterol.
belg., 2013, 76, 413-422). [Product Details...] |
|
Eosinophilic esophagitisPrice: €10,00 |
|
| Eosinophilic esophagitis is a chronic, immune-mediated disorder,
isolated to the esophagus. Current theory suggests that the
former may be caused by cell-mediated food hypersensitivity or
may be a subset of eosinophilic gastrointestinal disease, an autoimmune
disorder. During the last decade, the increasing prevalence
of EoE has been recognized in pediatric populations. Reports
support
the efficacy of dietary restriction or corticosteroid therapy.
Aditional
research is needed to determine etiology, allow earlier
clinical recognition and improve treatment. Because no single
symptom, endoscopic finding or histopathologic feature is pathognomonic,
the diagnosis can frequently be challenging. The current
article reviews the possible etiology, clinical presentation, diagnosis,
and treatment of this disorder, which has been called not only
allergic esophagitis (which may be the most important cause), but
also eosinophilic esophagitis, primary eosinophilic esophagitis, and
idiopathic eosinophilic esophagitis. (Acta gastroenterol.
belg., 2013,
76, 407-412). [Product Details...] |
|
Gastrointestinal stromal tumor of the stomach : progresses in diagnosis and treatmentPrice: €10,00 |
|
| Gastrointestinal stromal tumors (GISTs) are rare mesenchymal
smooth muscle neoplasms that can arise anywhere within the gastrointestinal
tract. Approximately 60-70% are located in the stomach.
Once considered variants of smooth muscle tumors, they are
now understood as originating from the interstitial cells of Cajal or
their stem cell precursors. The majority of GISTs (approximately
95%) express the CD117 antigen (KIT), a proto-oncogene product ;
85-95% of these neoplasms have mutations in the c-KIT gene ; only
5-7% has mutations in platelet-derived-growth factor α (PDGFRα).
GISTs can be asymptomatic and incidentally found during examination
for other pathologies or at autopsy. The most common
symptoms of gastric GIST are abdominal pain and bleeding. Diagnostic
work up consists of endoscopy with ultrasonography and
cross-sectional imaging studies (computed tomography and/or
magnetic resonance imaging).
Surgery remains the first-line treatment for localized gastric
GISTs. Both open and laparoscopic operations have been shown to
reduce recurrence rates and improve long-term survival. The use
of small-molecule selective tyrosine kinase receptor inhibitors has
revolutionized the treatment of advanced GISTs. (Acta gastroenterol.
belg., 2013, 76, 403-406) [Product Details...] |
|
Optimal use of proton pump inhibitors for treating acid peptic diseases in primary carePrice: €10,00 |
|
| Heartburn, reflux and epigastric pain are frequently encountered
symptoms in primary care medicine. Acid peptic diseases
such as peptic ulcer and gastrointestinal reflux disease have a high
prevalence, can have important impact on patient quality of life
and represent a considerable health care cost. Proton pump inhibitors
(PPIs) are the most potent pharmacological inhibitors of gastric
acid secretion currently available and are the mainstay medical
therapy for acid peptic diseases.
This review summarizes current evidence on treatment of acidpeptic
diseases with proton pump inhibitors and provides primary
care clinicians with best practice guidelines for optimal use of these
drugs. (Acta gastroenterol.
belg., 2013, 76, 393-402). [Product Details...] |
|
- «« Start
- « Prev
- 1
- Next »
- End »»
Acta Gastro-Enterologica Belgica is indexed in NCBI/PubMed.
Printed by Universa Press, Wetteren, Belgium. ©vzw/asbl Acta Gastro-Enterologica Belgica
Printed by Universa Press, Wetteren, Belgium. ©vzw/asbl Acta Gastro-Enterologica Belgica