Editor-in-Chief & Deputy Editor 2019-2021

 

Editor-in-Chief:

Nicolas LANTHIER

 

Deputy Editor:

Tim VANUYTSEL

 

Letters



Cryptosporidiosis in a patient with Crohn’s disease under anti-TNF treatment


Price: €10,00

Ulcerative Colitis (UC) and Crohn’s Disease CD), are chronic inflammatory bowel diseases (IBD) which may benefit from the treatment with biologic agents which target specific cytokines involved in inflammation (1). The anti-TNF therapy is the first biologic agent used in the treatment of complicated CD (2). Although the clinical efficacy of anti-TNF agents has been proven, their use may also be associated with an increased risk of opportunistic infections caused by bacteria, viruses and parasites (3). Cryptosporidiosis is a parasitic infection caused by Cryptosporidium Spp, clinically characterized by watery diarrhea, often profuse and prolonged, abdominal pain, nausea, vomiting, and fever. Cryptosporidium is an emerging protozoan parasite and it can be transmitted to humans from animals, from humans and from contaminated food or water. Disease severity varies according to the host general health: immunocompetent patients may develop a mild, selflimiting disease, while immunocompromised patients, may have severe and persistent symptoms, with gastrointestinal, biliary or respiratory manifestations (4). [Product Details...]



Fatal anaphylaxis of ranitidine injection : have we not learnt the lesson yet?


Price: €10,00

A 75-year-old man was admitted with complaints of fever and right upper quadrant pain for one day. He underwent a cholecystectomy three month ago. His conscious level was clear (Glasgow Coma Scale or GCS of E4V5M6) with temperature of 38.1 degree Celsius. His blood pressure was 107/53mmHg and pulse rate was 78 bpm. Physical examination showed tenderness without a rebounding pain over his right upper abdomen. His laboratory studies revealed leukocytosis with neutrophils predominant (WBC:11.79 103/uL, Neutrophil: 86.3%) and impaired liver function (AST:476 IU/L; ALT: 332 IU/L) with hyperbilirubinemia mainly of direct type (D-bilirubin:1.7 mg/dL; T-Bilirubin: 3.0 mg/dL). Neither elevation of cardiac enzymes (CPK:81IU/L, CKMB:1.73ng/mL, Troponin I [Product Details...]



Two cases of peripancreatic cystic lymphangiomas diagnosed by EUS-guided FNA


Price: €10,00

Case 1 : A 51-year old male was referred for evaluation of a large cystic mass inferior to the uncinate process of the pancreas and anterior to the 3rd portion of the duodenum. He was asymptomatic. No abdominal tenderness or mass was appreciated. MRCP and MRI of the pancreas showed a T2 hyperintense, microlobulated, multiseptated, and multi-cystic mass measuring 6.0 x 5.1 x 3.6 cm overall. Endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) of the cyst yielded 18 mL of milky-white fluid (Figure 1). Analysis of the cyst fluid revealed a CEA of 27.3 ng/mL, amylase of 47 U/L, and triglycerides of 6162 mg/dL. Cytology showed no malignant cells. A repeat MRI was obtained at a 1 year interval and showed no change in the lesion. [Product Details...]


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