Editor-in-Chief & Deputy Editor 2019-2021

 

Editor-in-Chief:

Nicolas LANTHIER

 

Deputy Editor:

Tim VANUYTSEL

 

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Letters


A new cause of acute hepatitis : Gemifloxacin.


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We wish to draw attention to a largely unreported side effect of the drug Gemifloxacin, drug induced hepato - toxicity, which has been observed in our institution. Gemifloxacin is a recently introduced fluoroquinolone antibiotic which is frequently used for its broad spectrum. In generally gemifloxacin is well tolerated with most side effects being comparable with other compounds. The most frequent side effects are abdominal pain, diarrhoea, and headaches (1). Factors that determine individual vulnerability to liver toxicity may include age, genetic predisposition, systemic disease, nutritional status and concomitant exposure to other hepatotoxic agents. Most of the druginduced liver injuries are idiosyncratic reactions and occur in an unpredictable manner. These reactions may occur at any time during exposure to a drug (2). [Product Details...]


An unusual complication of nasogastric tube


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Multiple case reports of complications of malpositioned feeding tubes continue to surface. Most are due to inadvertent placement in the respiratory tract. Isolated reports of a nasally placed tube entering the brain following head injury continue to occur, as do reports of esophageal and gastric perforation in neonates. A recent study showed that malpositioned tubes are not routinely recorded in risk management databases (1). But maybe the most important complication of nasogastric tubes (NGT) is GI bleeding. It has been reported that prolonged use of NGT can even result in life-threatening aortoesophageal fistula formation in patients with a double aortic arch (2). Herein we report a case with a buried NGT and GI hemorrhage after the unsuccessful attempt to remove the NGT. [Product Details...]


Choledochal cyst and crossed fused ectopic kidney – a hitherto unknown association


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Choledochal cyst is an uncommon biliary tract anomaly defined as dilatation of extrahepatic bile tree with or without intrahepatic biliary dilatation. It is one of the important differential diagnosis of jaundice and abdominal pain in the pediatric population. Though association with various developmental anomalies is already known, its combination with Crossed fused ectopic kidney has not been reported before in the literature to the best of our knowledge. [Product Details...]


Collagenous colitis and ileitis under treatment with duloxetine


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Collagenous colitis (CC) is a disease that causes chronic diarrhea, that could be diagnosed with a normal colonoscopic examination. Diagnosis is based on the histopathologic examination of the mucosa containing thickened subepithelial collagen layer (1). Etiology and pathophsiology of CC are not known exactly (2). In this article, the first case with CC and CI (Collagenous ileitis) associated with duloxetine [Serotonin norephinefrine reuptake inhibitor (SNRI)] treatment for major depression is presented. [Product Details...]


Gangliocytic Paraganglioma of the duodenum : A rare entity


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Gangliocytic paraganglioma (GP) is a rare condition and the available data consist mainly of case descriptions. The lesion was first described by Dahl et al. in 1957 (1). The term GP was introduced by Kepes and Zcharias and is derived from his histological features of neurendocrine tumor, paraganglioma and ganglio - neuroma. The tumor is typically located in the second or third part of the duodenum (2). [Product Details...]


Multicentric CD34 negative epithelioid angiosarcoma of the digestive system


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We would like to report a particular case of a gastro - intestinal angiosarcoma that recently occurred in our hospital. A 74-year-old male was referred to our surgical department because of severe anemia due to repeated episodes of melena and right cervical swelling associated with an oral lump of the upper dental arcade which was bleeding profusely (Fig. 1). A gastroscopy showed some haemorrhagic gastric and duodenal polyps, some of which were removed. A colonoscopy revealed the presence of multiple rectal, sigmoid and colonic polyps grossly similar to the gastric ones (Fig. 1). A total body CT scan showed multiple nodules, localized both in peritoneum, next to duodenum, spleen and mesenteric artery and in retro-peritoneum. [Product Details...]


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