Editor-in-Chief, Deputy Editor 2017-2019

 

Editor-in-Chief:

Tom MOREELS

 

Deputy Editor:

Nicolas LANTHIER

 

Symposium



Adult liver transplantation at UCL : update 2002


Price: €10,00

The authors present the results of a single centre study of 587 liver transplants performed in 522 adults during the period 1984-2002. Results have improved significantly over time due to better pre-, peri- and post-transplant care. One, five, ten and fifteen year actuarial survivals for the whole patient group are 81.2 ; 69.8 ; 58.9 and 51.2%. The high incidence of de novo tumors (12.3%), of cardiovascular diseases (7.5%) and of end-stage renal function (3.6%) should be further incentives to tailor the immunosuppression to the individual patient and to direct the attention of the transplant physician to the long-term quality of life of the liver recipient. [Product Details...]



Ethical perspectives about organ allocation for transplantation


Price: €10,00

The ethical questions suggested by the allocation of organs for transplantation can be assembled around the notion of justice. It is a domain of health care in which there is a chronic lack of resources, but for patients whose life is at stake, sometimes at short term. It has similarities with the triage, imposed in some conditions of emergency medicine, at war or during civil catastrophes. The question will be approached from the points of view of the main stakeholders. [Product Details...]



Genetic cholestatic liver diseases : The example of progressive familial intrahepatic cholestasis and related disorders


Price: €10,00

No abstract available. [Product Details...]



History of pediatric liver transplantation in Europe


Price: €10,00

No abstract available. [Product Details...]



Introduction


Price: €10,00

No abstract available. [Product Details...]



Introduction


Price: €10,00

No abstract available. [Product Details...]



The paediatric liver transplantation program at the Université catholique de Louvain(1). (1) Presented at the Symposium “Liver transplantation and its alternatives in the third millennium”, in honour of professor Jean-Bernard Otte (Brussels,4 October 2


Price: €10,00

The Paediatric Liver Transplant Program at Saint-Luc University Clinics constitutes a substantial single centre experience, including 667 transplantations performed between March 1984 and April 2003, and the history of this program reflects the tremendous progress in this field since twenty years. Liver transplantation in children constitutes a considerable undertaking and its results depend on multiple, intermingled risk factors. An analysis of the respective impact of several surgical and immunological parameters on patient/graft outcome and allograft rejection after paediatric liver transplantation showed a significant learning curve effect as well as the respective impact of pre-transplant diagnosis on survival and of primary immunosuppression on the rejection incidence. The introduction of living related liver transplantation in 1993 not only permitted to provide access to liver replacement in as many as 74% more candidate recipients, but also resulted in better graft survival and reduced retransplantation rate. The results of a recent pilot study suggest that steroid avoidance is not harmful, and could even be beneficial for paediatric liver recipients, particularly regarding growth, and that combining tacrolimus with basiliximab (anti-CD25 chimeric monoclonal antibody) for steroid substitution appears to constitute a safe alternative in this context. The long-term issues represent the main future challenges in the field, including the possibility of a full rehabilitation through immunosuppression withdrawal and tolerance induction, the development of adolescence transplant medicine, and the risk of early atherogenesis in the adulthood. [Product Details...]



The psychological challenge of paediatric organ transplantation : gift and incorporation


Price: €10,00

The specific feature of organ transplantation is the confrontation of the patient with a body part not being his own and coming from somebody else. Thus the psychological challenge of transplantation will be the gift and incorporation of the graft. The given organ confronts the patients with mental manifestations related to emotions of grieving and guilt, most constantly directed to the donor himself. It can also cause a fantastical imagination related to the idea of having to some extent inherited the character of the donor. This very special gift relationship has to be questioned, as it can be interpreted in terms of a tyranny of the dept. A dept the recipient will never be able to reimburse. In this context the contribution of sociological knowledge is determining. It makes it possible to reconsider the problem, and to discover that a gift relationship offers transplant patients much vaster possibilities than a materialistic conception of the gift, based on the dept, would do. [Product Details...]



Treatment of hepatocellular carcinoma at the dawn of the third millennium : liver transplantation and its alternatives


Price: €10,00

Hepatocellular carcinoma is one of the most frequent tumors worldwide, and its frequency is increasing. The management of hepatocellular carcinoma has changed in recent years, this because screening allows to discover tumors at an earlier stage, and because of effective treatments are available, such as liver transplantation, liver resection, percutaneous ablation and transarterial chemoembolization. Each one of these treatments has its own advantages and drawbacks, and range of application according to the stage of the tumor and of the underlying liver disease. This review summarizes the recent progress in the management of HCC and the practice in our unit. [Product Details...]



Viral hepatitis B, C and D


Price: €10,00

No abstract available. [Product Details...]


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